Nuclear-encoded regulatory proteins control mitochondrial translation. A few, however, are encoded by the mitochondrial DNA (mtDNA) and are produced by the mitochondrial translation machinery.
Eukaryotic translation initiation factors in trypanosomatids display a fascinating divergence from those in higher eukaryotes. Foundational research has revealed that these parasites possess multiple ...
In all organisms, mRNA-directed protein synthesis is catalysed by ribosomes. Although the basic aspects of translation are preserved in all kingdoms of life, important differences are found in the ...
Kazuki Saito, Kan Kobayashi, Miki Wada, Izumi Kikuno, Akira Takusagawa, Masahiro Mochizuki, Toshio Uchiumi, Ryuichiro Ishitani, Osamu Nureki, Koichi Ito, Paul Schimmel Proceedings of the National ...
It is unlikely that Shakespeare was thinking of ribosomes when he warned against hastiness. But it turns out, for ribosomes too, “wisely and slow” does not really cut it as they go about their ...
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Proteins are essential biological molecules that perform a vast array of functions crucial for life, from catalyzing ...
Only recently has the ribosome - one of the oldest molecular machines in evolutionary terms - been recognized as an active regulator of gene expression at the level of protein biosynthesis. This is an ...