G-quadruplexes are non-canonical secondary structures formed by guanine-rich sequences in DNA and RNA. Four guanines assemble into a planar tetrad through Hoogsteen hydrogen bonding, and stacked ...
IN 1962, when David R. Davies was in his 30s, he and two coworkers at the National Institutes of Health proposed that short, guanine-rich stretches of DNA could assume unusual structures. On the basis ...
This image is based on an x-ray crystal structure of a G-quadruplex formed from the DNA sequence found in human genomes. This image is based on an x-ray crystal structure of a G-quadruplex formed from ...
DNA, the genetic material compacted in chromosomes, stores information to regulate all the cell processes in the body. Two decades ago, in addition to the widely known Watson-Crick double helix model ...
Designers of cancer drugs have begun to aim their arrows at an up-and-coming series of targets in the human genome: quadruplexes, a family of DNA structures that form in sites that switch genes on ...
In one of the biggest residential apartment deals in the country, Bollywood actor Ranveer Singh has bought a sea-facing quadruplex in suburban Bandra for Rs 119 crore, industry sources said on Monday.
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